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CAS 112-35-6 | m-PEG3-OH

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Common Namem-PEG3-OH
CAS Number112-35-6Molecular Weight164.199
Density1.0±0.1 g/cm3Boiling Point233.9±20.0 °C at 760 mmHg
Molecular FormulaC7H16O4Melting Point-44ºC
MSDSChineseUSAFlash Point95.3±21.8 °C

Names

Nametriethylene glycol monomethyl ether
SynonymMore Synonyms

m-PEG3-OH BiologicalActivity

Descriptionm-PEG3-alcohol is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
Related CatalogResearch Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker
Target

PEGs

In VitroPROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins

Chemical & Physical Properties

Density1.0±0.1 g/cm3
Boiling Point233.9±20.0 °C at 760 mmHg
Melting Point-44ºC
Molecular FormulaC7H16O4
Molecular Weight164.199
Flash Point95.3±21.8 °C
Exact Mass164.104858
PSA47.92000
LogP-1.51
Vapour density5.66 (vs air)
Vapour Pressure0.0±1.0 mmHg at 25°C
Index of Refraction1.427
InChIKeyJLGLQAWTXXGVEM-UHFFFAOYSA-N
SMILESCOCCOCCOCCO

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
KL6390000
CHEMICAL NAME :
Ethanol, 2-(2-(2-methoxyethoxy)ethoxy)-
CAS REGISTRY NUMBER :
112-35-6
BEILSTEIN REFERENCE NO. :
1700198
LAST UPDATED :
199710
DATA ITEMS CITED :
11
MOLECULAR FORMULA :
C7-H16-O4
MOLECULAR WEIGHT :
164.23
WISWESSER LINE NOTATION :
Q2O2O2O1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Open irritation test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 23,95,1962
TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,634,1986
TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration into the eye
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,634,1986 ** ACUTE TOXICITY DATA **
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
11300 uL/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 23,95,1962
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
7100 uL/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 23,95,1962 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M0892 No. of Facilities: 13261 (estimated) No. of Industries: 85 No. of Occupations: 32 No. of Employees: 80404 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M0892 No. of Facilities: 2416 (estimated) No. of Industries: 22 No. of Occupations: 29 No. of Employees: 18956 (estimated) No. of Female Employees: 9842 (estimated)

Safety Information

Personal Protective EquipmentEyeshields;Gloves
Hazard CodesXi
Safety PhrasesS24/25-S22
RIDADRNONH for all modes of transport
WGK Germany1
RTECSKL6390000
HS Code2909499000

Customs

HS Code2909499000
Summary2909499000. ether-alcohols and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:5.5%. General tariff:30.0%

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Synonyms

UNII-DN0P4Q4I16
Ethanol, 2-(2-(2-methoxyethoxy)ethoxy)-
Triethylene glycol monomethyl ether
3,6,9-Trioxa-1-decanol
Triglycol monomethyl ether
2-(2-(2-Methoxyethoxy)ethoxy)ethanol
Methoxytriglycol
triethylene glycol methyl ether
Methoxytriethylene glycol
2-[2-(2-Methoxyethoxy)ethoxy]ethanol
Ethanol, 2-[2-(2-methoxyethoxy)ethoxy]-
Methyltrioxitol
Methyl Triglycol
Methyltriglycol
MFCD00002875
Methyl triethylene glycol
EINECS 203-962-1

Declaration: The products displayed on this website are intended exclusively for industrial applications or scientific research. They are not intended for medical, pharmaceutical, or food use. In accordance with applicable laws and regulations, purchasing organizations must hold valid qualifications and approvals.

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