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| Classification | Catalysts and Additives |
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| Common Name | Triethylene glycol monodecyl ether | ||
|---|---|---|---|
| CAS Number | 4669-23-2 | Molecular Weight | 290.43900 |
| Density | 0.936 g/mL at 20ºC(lit.) | Boiling Point | / |
| Molecular Formula | C16H34O4 | Melting Point | / |
| MSDS | ChineseUSA | Flash Point | / |
| Name | 2-[2-(2-decoxyethoxy)ethoxy]ethanol |
|---|---|
| Synonym | More Synonyms |
| Description | Triethylene glycol monodecyl ether is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | Research Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker |
| Target | PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References | [1]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985. |
| Density | 0.936 g/mL at 20ºC(lit.) |
|---|---|
| Molecular Formula | C16H34O4 |
| Molecular Weight | 290.43900 |
| Exact Mass | 290.24600 |
| PSA | 47.92000 |
| LogP | 3.16920 |
| Index of Refraction | n20/D 1.449 |
| InChIKey | UKODLHVFJRCQME-UHFFFAOYSA-N |
| SMILES | CCCCCCCCCCOCCOCCOCCO |
| Storage condition | 2-8°C |
| Personal Protective Equipment | Eyeshields;Gloves |
|---|---|
| Safety Phrases | 24/25 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| The action of alcohols and other non-ionic surface active substances on the sodium current of the squid giant axon. J. Physiol. 341 , 411, (1983) The effects of several n-alkanols and n-alkyl oxyethylene alcohols, methyl octanoate, glycerol 1-monooctanoate and dioctanoyl phosphatidylcholine on the ionic currents and electrical capacity of the s... | |
| The effect of surfactants upon rat peritoneal mast cells in vitro. Food Chem. Toxicol. 14 , 425, (1976) |
| Decyltriglycol |
| Triethylene glycol monodecyl ether |
| triethylene glycol monodecyl ether |
| Emulgin BL 309 |
| C10E3 |
| 3,6,9-trioxa-1-nonadecanol |
| n-decyl triethylene glycol monoether |
| Triethyleneglycol monodecyl ether solution |
| triethylene glycol mono-n-decyl ether |
| Decyl triethylene glycol ether |
| Triethyleneglycol monodecyl ether 1 mM solution |
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