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CAS 131-53-3 | dioxybenzone

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Common Namedioxybenzone
CAS Number131-53-3Molecular Weight244.243
Density1.3±0.1 g/cm3Boiling Point375.0±0.0 °C at 760 mmHg
Molecular FormulaC14H12O4Melting Point73-75 °C(lit.)
MSDSChineseUSAFlash Point146.0±18.6 °C
Symbol
GHS07
Signal WordWarning

Names

Name2,2'-Dihydroxy-4-methoxybenzophenone
SynonymMore Synonyms

dioxybenzone BiologicalActivity

DescriptionDioxybenzone is an organic compound used in sunscreen to block UVB and short-wave UVA (ultraviolet) rays.
Related CatalogSignaling Pathways >>Others >>OthersResearch Areas >>Others

Chemical & Physical Properties

Density1.3±0.1 g/cm3
Boiling Point375.0±0.0 °C at 760 mmHg
Melting Point73-75 °C(lit.)
Molecular FormulaC14H12O4
Molecular Weight244.243
Flash Point146.0±18.6 °C
Exact Mass244.073563
PSA66.76000
LogP3.93
Vapour Pressure0.0±0.8 mmHg at 25°C
Index of Refraction1.624
InChIKeyMEZZCSHVIGVWFI-UHFFFAOYSA-N
SMILESCOc1ccc(C(=O)c2ccccc2O)c(O)c1
StabilityStable. Incompatible with strong oxidizing agents.

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DJ1049500
CHEMICAL NAME :
Benzophenone, 2,2'-dihydroxy-4-methoxy-
CAS REGISTRY NUMBER :
131-53-3
BEILSTEIN REFERENCE NO. :
2055461
LAST UPDATED :
199701
DATA ITEMS CITED :
6
MOLECULAR FORMULA :
C14-H12-O4
MOLECULAR WEIGHT :
244.26
WISWESSER LINE NOTATION :
QR BVR BQ DO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Rodent - mouse Lymphocyte
DOSE/DURATION :
32 ug/plate
REFERENCE :
JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. Volume(issue)/page/year: 2(5),35,1983 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M2989 No. of Facilities: 236 (estimated) No. of Industries: 3 No. of Occupations: 4 No. of Employees: 1482 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M2989 No. of Facilities: 537 (estimated) No. of Industries: 4 No. of Occupations: 5 No. of Employees: 4315 (estimated) No. of Female Employees: 183 (estimated)

Safety Information

Symbol
GHS07
Signal WordWarning
Hazard StatementsH315-H319-H335
Precautionary StatementsP261-P305 + P351 + P338
Personal Protective Equipmentdust mask type N95 (US);Eyeshields;Gloves
Hazard CodesXi:Irritant;
Risk PhrasesR36/37/38
Safety PhrasesS26-S36
RIDADRNONH for all modes of transport
WGK Germany3
RTECSDJ1049500
HS Code2914509090

Customs

HS Code2914509090
SummaryHS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

Articles8

More Articles
Metabolism of UV-filter benzophenone-3 by rat and human liver microsomes and its effect on endocrine-disrupting activity.

Toxicol. Appl. Pharmacol. 282(2) , 119-28, (2015)

Benzophenone-3 (2-hydroxy-4-methoxybenzophenone; BP-3) is widely used as sunscreen for protection of human skin and hair from damage by ultraviolet (UV) radiation. In this study, we examined the metab...

Oral chemoprevention of skin cancer in mice by benzophenone sunscreens dioxybenzone and octabenzone in drinking water.

Anticancer Res. 33(6) , 2535-40, (2013)

Sunscreen compounds with added benefit of skin cancer prevention have both public and commercial interests. Our earlier study using the Epstein-Barr virus early antigen in vitro assay reported on skin...

Rapid determination of nine parabens and seven other environmental phenols in urine samples of German children and adults.

Int. J. Hyg. Environ. Health 217(8) , 845-53, (2014)

We developed a fast, selective and sensitive on-line LC/LC-MS/MS method for the simultaneous determination of nine parabens and seven environmental phenols in urine. Parabens are widely used as antimi...

Synonyms

2,2′-dihydroxy-4-methoxybenzophenone
dioxybenzone
MFCD00002218
UF 2
EINECS 205-026-8
2,2-Dihydroxy-4-Methoxybenzophenone
(2-Hydroxy-4-methoxyphenyl)(2-hydroxyphenyl)methanone
2,2'-Hydroxy-4-methoxybenzophenone
2,2'-dihydroxy-4-methoxy-benzophenone
cyasorbuv24
Spectra-sorb UV 24
advastab47
2,2'-Dihydroxy-4-methoxybenzophenone
Cyasorb UV 24
Methanone, (2-hydroxy-4-methoxyphenyl)(2-hydroxyphenyl)-
uv24
benzophenone-8
UNII-B762XZ551X
2,2'-DIBROMODIETHYL ETHER
2,2'-dihydroxy-4-methoxy benzophenone
4-Methoxy-2,2'-dihydroxybenzophenone
dihydroxy-4-methoxybenzophenone
Cyasorb

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