CAS 25990-96-9 | Octaethylene glycol monomethyl ether

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Common Name	Octaethylene glycol monomethyl ether
CAS Number	25990-96-9	Molecular Weight	384.462
Density	1.1±0.1 g/cm3	Boiling Point	454.0±40.0 °C at 760 mmHg
Molecular Formula	C₁₇H₃₆O₉	Melting Point	/
MSDS	/	Flash Point	228.4±27.3 °C

Names

Name	2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol
Synonym	More Synonyms

Octaethylene glycol monomethyl ether BiologicalActivity

Description	Octaethylene glycol monomethyl ether is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Chemical & Physical Properties

Density	1.1±0.1 g/cm3
Boiling Point	454.0±40.0 °C at 760 mmHg
Molecular Formula	C₁₇H₃₆O₉
Molecular Weight	384.462
Flash Point	228.4±27.3 °C
Exact Mass	384.235931
PSA	94.07000
LogP	-3.30
Vapour Pressure	0.0±2.5 mmHg at 25°C
Index of Refraction	1.451
InChIKey	SZGNWRSFHADOMY-UHFFFAOYSA-N
SMILES	COCCOCCOCCOCCOCCOCCOCCOCCO
Storage condition	2-8°C

Safety Information

HS Code	2909499000

Customs

HS Code	2909499000
Summary	2909499000. ether-alcohols and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:5.5%. General tariff:30.0%

Synonyms

2,5,8,11,14,17,20,23-Octaoxapentacosan-25-ol

3,6,9,12,15,18,21,24-Octaoxapentacosan-1-ol

polyethylene(n ca. 8)glycol monomethyl ether

23-methoxy-3,6,9,12,15,18,21-heptaoxa-tricosan-1-ol

Octaethylene Glycol MonoMethyl Ether

O-methyl-octaethylene glycol

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