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CAS 116355-84-1 | fumonisin B2

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Common Namefumonisin B2
CAS Number116355-84-1Molecular Weight705.831
Density1.2±0.1 g/cm3Boiling Point864.4±65.0 °C at 760 mmHg
Molecular FormulaC34H59NO14Melting Point<3200(dec)
MSDSChineseUSAFlash Point476.6±34.3 °C
Symbol
GHS02, GHS07
Signal WordDanger

Names

Namefumonisin B2
SynonymMore Synonyms

fumonisin B2 BiologicalActivity

DescriptionFumonisin B2, a mycotoxin produced by Fusarium moniliforme in various grains, is a potent inhibitor of sphingosine N-acyltransferase (ceramide synthase) and disrupts de novo sphingolipid biosynthesis[1][2].
Related CatalogResearch Areas >>InfectionSignaling Pathways >>Others >>Others
Target

Sphingosine N-acyltransferase[2]

References

[1]. Henry MH, et al. The toxicity of fumonisin B1, B2, and B3, individually and in combination, in chicken embryos. Poult Sci. 2001 Apr;80(4):401-7.

[2]. Shephard GS, et al. Disruption of sphingolipid metabolism in non-human primates consuming diets of fumonisin-containing Fusarium moniliforme culture material. Toxicon. 1996 May;34(5):527-34.

[3]. Wei T, et al. Natural occurrence of fumonisins B1 and B2 in corn in four provinces of China. Food Addit Contam Part B Surveill. 2013;6(4):270-4.

Chemical & Physical Properties

Density1.2±0.1 g/cm3
Boiling Point864.4±65.0 °C at 760 mmHg
Melting Point<3200(dec)
Molecular FormulaC34H59NO14
Molecular Weight705.831
Flash Point476.6±34.3 °C
Exact Mass705.393555
PSA268.28000
LogP4.39
Vapour Pressure0.0±0.6 mmHg at 25°C
Index of Refraction1.520
InChIKeyUXDPXZQHTDAXOZ-FWPUDPCBSA-N
SMILESCCCCC(C)C(OC(=O)CC(CC(=O)O)C(=O)O)C(CC(C)CCCCCCC(O)CC(O)C(C)N)OC(=O)CC(CC(=O)O)C(=O)O

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TZ8335000
CHEMICAL NAME :
1,2,3-Propanetricarboxylic acid, 1,1'-(1-(2-amino-9,11-dihydroxy-2-methyltridecyl)-2-( 1- methylpentyl)-1,2-ethanediyl) ester
CAS REGISTRY NUMBER :
116355-84-1
LAST UPDATED :
199510
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C34-H59-N-O14
MOLECULAR WEIGHT :
705.94

Safety Information

Symbol
GHS02, GHS07
Signal WordDanger
Hazard StatementsH225-H319
Precautionary StatementsP210-P305 + P351 + P338-P370 + P378-P403 + P235
Personal Protective EquipmentEyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard CodesT+: Very toxic;
Risk PhrasesR26/27/28
Safety PhrasesS22;S45;S36/S37/S39
RIDADRUN 2811 6
WGK Germany3
RTECSTZ8335000
HS Code29221990

Articles29

More Articles
Lipid metabolism of commercial layers fed diets containing aflatoxin, fumonisin, and a binder.

Poult. Sci. 92(8) , 2077-83, (2013)

Aflatoxins (AF) and fumonisins (FU) are a major problem faced by poultry farmers, leading to huge economic losses. This experiment was conducted to determine the effects of AF (1 mg/kg of feed) and FU...

Surveys of rice sold in Canada for aflatoxins, ochratoxin A and fumonisins.

Food Addit. Contam. Part A. Chem. Anal. Control. Expo. Risk Assess. 28(6) , 767-74, (2011)

Approximately 200 samples of rice (including white, brown, red, black, basmati and jasmine, as well as wild rice) from several different countries, including the United States, Canada, Pakistan, India...

Assessment of fumonisins B1 and B2 levels in commercial maize-based food products by liquid chromatography with fluorimetric detection and postcolumn chemical derivatization.

J. Food Sci. 76(1) , T1-4, (2011)

The occurrence of the fumonisins B(1) and B(2) in maize-based food products marketed in Italy was examined. A simply and reliable chromatographic method with fluorimetric detection and postcolumn o-ph...

Synonyms

fumonisin b2solution
FUMONISIN B3
FUMONISIN B2
EINECS 201-067-0
MFCD00133350
FB2,Fumonisin B2,Ready Made
Fumonisin B2 from Fusarium moniliforme
FB2
1,2,3-Propanetricarboxylic acid, 1,1'-[1-(12-amino-9,11-dihydroxy-2-methyltridecyl)-2-(1-methylpentyl)-1,2-ethanediyl] ester
2,2'-{(19-Amino-16,18-dihydroxy-5,9-dimethyl-6,7-icosanediyl)bis[oxy(2-oxo-2,1-ethanediyl)]}disuccinic acid
Diquat-d4 Dibromide

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