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CAS 9003-01-4 | Polyacrylic acid

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Common NamePolyacrylic acid
CAS Number9003-01-4Molecular Weight2000(Average)
Density1.09 (30% aq.)Boiling Point116ºC
Molecular Formula(C3H4O2)xMelting Point106ºC
MSDSChineseUSAFlash Point61.6ºC
Symbol
GHS08
Signal WordDanger

Names

Namepoly(acrylic acid) macromolecule
SynonymMore Synonyms

Polyacrylic acid BiologicalActivity

DescriptionPoly(acrylic acid) is a polyacrylic acid with a molecular weight of 2000.
Related CatalogResearch Areas >>OthersSignaling Pathways >>Others >>Others

Chemical & Physical Properties

Density1.09 (30% aq.)
Boiling Point116ºC
Melting Point106ºC
Molecular Formula(C3H4O2)x
Molecular Weight2000(Average)
Flash Point61.6ºC
Exact Mass72.02110
PSA37.30000
LogP0.25700
Index of Refractionn20/D 1.442
Water SolubilitySoluble in water.

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AT4680000
CHEMICAL NAME :
Acrylic acid, polymers
CAS REGISTRY NUMBER :
9003-01-4
LAST UPDATED :
199710
DATA ITEMS CITED :
14
MOLECULAR FORMULA :
(C3-H4-O2)x
MOLECULAR WEIGHT :
168.06
WISWESSER LINE NOTATION :
/*1Y*VQ/

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ACIEAY Angewandte Chemie, International Edition in English. (VCH Pub., Inc., 303 NW 12th Ave., Deerfield Beach, FL 33441) V.1- 1962- Volume(issue)/page/year: 14,94,1975
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
4600 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FRPPAO Farmaco, Edizione Pratica. (Casella Postale 227, 27100 Pavia, Italy) V.8-43 1953-88 For publisher information, see FRMCE8 Volume(issue)/page/year: 25,721,1970
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
39 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 21,652,1978
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
70 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ZMEIAV Zhurnal Mikrobiologii, Epidemiologii i Immunobiologii. Journal of Microbiology, Epidemiology, and Immunology. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.14- 1935- Volume(issue)/page/year: (9),14,1979
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 114,258,1958 *** REVIEWS *** IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 19,47,1979 IARC Cancer Review:Animal No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 19,47,1979 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 82129 No. of Facilities: 2084 (estimated) No. of Industries: 44 No. of Occupations: 55 No. of Employees: 34007 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X7610 No. of Facilities: 31268 (estimated) No. of Industries: 198 No. of Occupations: 162 No. of Employees: 571954 (estimated) No. of Female Employees: 232712 (estimated)

Safety Information

Symbol
GHS08
Signal WordDanger
Hazard StatementsH340-H350
Precautionary StatementsP201-P308 + P313
Personal Protective EquipmentEyeshields;Gloves;half-mask respirator (US);multi-purpose combination respirator cartridge (US)
Hazard CodesC: Corrosive;T: Toxic;Xi: Irritant;
Risk Phrases45-46-34-36/37/38
Safety PhrasesS24/25
RIDADRUN 3265 8/PG 3
WGK Germany3
RTECSAT4680000
HS Code3906909090

Customs

HS Code3906909090

Articles35

More Articles
Cyclodextrin-crosslinked poly(acrylic acid): adhesion and controlled release of diflunisal and fluconazole from solid dosage forms.

AAPS PharmSciTech 14(1) , 301-11, (2013)

The controlled release of diflunisal and fluconazole from tablets made of novel polymers, poly(acrylic acid) (PAA) crosslinked with either β-cyclodextrin (βCD) or hydroxypropyl-βCD (HPβCD), was invest...

Cyclodextrin-crosslinked poly(acrylic acid): Synthesis, physicochemical characterization and controlled release of diflunisal and fluconazole from hydrogels.

Int. J. Pharm. 444(1-2) , 175-84, (2013)

The aim of this work was to develop mucoadhesive hydrogels with variable drug delivery properties by crosslinking poly(acrylic acid) (PAA) with cyclodextrins (CDs). CD-PAA polymers with high CD conten...

Chest wall reconstruction using biomaterials.

Ann. Thorac. Surg. 95(3) , 1050-6, (2013)

Skeletal chest wall reconstruction can be a challenge, depending on the indication, location, and health of the patient; various materials are available. Recently, biomaterials that are remodelable (b...

Synonyms

PAA
Poly(acrylic acid)
Propenoic acid polymer
EINECS 618-347-7
Acrylic acid polymer
MFCD00084394
2-Propenoic acid homopolymer
Carbomer 940
Polyacrylic acid
Carbomer 934

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