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CAS 3055-97-8 | 3,6,9,12,15,18,21-Heptaoxatritriacontan-1-ol

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Common Name3,6,9,12,15,18,21-Heptaoxatritriacontan-1-ol
CAS Number3055-97-8Molecular Weight494.702
Density1.0±0.1 g/cm3Boiling Point553.9±45.0 °C at 760 mmHg
Molecular FormulaC26H54O8Melting Point27-29 °C
MSDSChineseUSAFlash Point288.8±28.7 °C
Symbol
GHS07
Signal WordWarning

Names

NameDodecylheptaglycol
SynonymMore Synonyms

BiologicalActivity

DescriptionDodecylheptaglycol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related CatalogResearch Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker
Target

PEGs

In VitroPROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.

Chemical & Physical Properties

Density1.0±0.1 g/cm3
Boiling Point553.9±45.0 °C at 760 mmHg
Melting Point27-29 °C
Molecular FormulaC26H54O8
Molecular Weight494.702
Flash Point288.8±28.7 °C
Exact Mass494.381866
PSA84.84000
LogP2.90
Vapour Pressure0.0±3.4 mmHg at 25°C
Index of Refraction1.458
InChIKeyDWHIUNMOTRUVPG-UHFFFAOYSA-N
SMILESCCCCCCCCCCCCOCCOCCOCCOCCOCCOCCOCCO
Storage condition2-8°C

Safety Information

Symbol
GHS07
Signal WordWarning
Hazard StatementsH315-H319-H335
Precautionary StatementsP261-P305 + P351 + P338
Personal Protective Equipmentdust mask type N95 (US);Eyeshields;Gloves
Hazard CodesXi: Irritant;
Risk PhrasesR36/37/38
Safety PhrasesS26-S36
RIDADRNONH for all modes of transport
WGK Germany2
HS Code2909499000

Customs

HS Code2909499000
Summary2909499000. ether-alcohols and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:5.5%. General tariff:30.0%

Articles1

More Articles
Y. Ichikawa et al.

J. Ferment. Technol. 56 , 403, (1978)

Synonyms

LAURETH-7
HEPTAETHYLENE GLYCOL DODECYL ETHER
3,6,9,12,15,18,21-Heptaoxatritriacontan-1-ol
3,6,9,12,15,18,21-heptaoxatritriacontanol
MFCD00043065
Heptaethylene glycol monododecyl ether
laureth-7 oxyethylene ether
HEPTAETHYLENEGLYCOL-N-DODECYLETHER
EINECS 221-283-9
dodecylalcohol heptaethoxylate
C12E7
POLYOXYETHYLENE 7 LAURYL ETHER
20-dodecyloxy-3,6,9,12,15,18-hexaoxa-eicosan-1-ol
HEPTAOXYETHYLENE MONO-N-DODECYL ETHER

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